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Reproduced with permission from: Carol Tang
The immunofluorescence pictures show a mix of brain tumour stem cells and progenitors isolated from a glioblastoma multiforme (GBM) sample. Nestin expression marks neural precursors. Musashi-1 is a marker for self-renewal, the ability to propagate itself. CD133 is currently the only known marker for brain tumour stem cells. CD133-expressing cells have been shown to initiate and sustain glioma xenografts in immunocompromised mouse models. (Blue staining marks nuclei.)
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Original Articles
Multivoxel MR Spectroscopic Imaging - Distinguishing Intracranial Tumours from Non-neoplastic Disease
Veena Arpit Nagar, Jieru Ye, Maosheng Xu, Wai-Hoe Ng, Tseng-Tsai Yeo, Peck-Leong Ong, CC Tchoyoson Lim
Epidemiology, Management and Treatment Outcome of Medulloblastoma in Singapore
Mei-Yoke Chan, Wan-Yee Teo, Wan-Tew Seow, Ah-Moy Tan
Anaesthetic Management of Awake Craniotomy for Tumour Resection
Jee-Jian See, Thomas WK Lew, Tong-Kiat Kwek, Ki-Jinn Chin, Mary FM Wong, Qui-Yin Liew, Siew-Hoon Lim, Hwee-Shih Ho, Yeow Chan, Genevieve PY Loke, Vincent ST Yeo
Awake Craniotomy Under Local Anaesthesia and Monitored Conscious Sedation for Resection of Brain Tumours in Eloquent Cortex - Outcomes in 20 Patients
David Low, Ivan Ng, Wai-Hoe Ng
Optimising Radiation Therapy Techniques for Tumours of the Central Nervous System
Michael F Back, Shaun Baggarley, Eileen Park, Ren Wei
Improved Median Survival for Glioblastoma Multiforme Following Introduction of Adjuvant Temozolomide Chemotherapy
Michael F Back, Emily LL Ang, Wai-Hoe Ng, Siew-Ju See, CC Tchoyoson Lim, SP Chan, Tseng-Tsai Yeo
Salvage Chemotherapy in Progressive High-grade Astrocytoma
Siew-Ju See, Albert Ty, Meng-Cheong Wong
Improvements in Quality of Care Resulting From a Formal Multidisciplinary Tumour Clinic in the Management of High-grade Glioma
Michael F Back, Emily LL Ang, Wai-Hoe Ng, Siew-Ju See, Lim CC Tchoyoson, Lee-Lee Tay, Tseng-Tsai Yeo
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